Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic risk

Osteoarthritis (OA) is a common, painful and debilitating disease of articulating joints resulting from the age-associated loss of cartilage. Well-powered genetic studies have identified a number of DNA polymorphisms that are associated with OA susceptibility. Like most complex trait loci, these OA...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Rushton, Michael D., Reynard, Louise N., Young, David A., Shepherd, Colin, Aubourg, Guillaume, Gee, Fiona, Darlay, Rebecca, Deehan, David, Cordell, Heather J., Loughlin, John
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664171/
https://ncbi.nlm.nih.gov/pubmed/26464490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv433
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