Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing

Mitochondrial dysfunction is a well-established cause of sensorineural deafness, but the pathophysiological events are poorly understood. Non-syndromic deafness and predisposition to aminoglycoside-induced deafness can be caused by specific mutations in the 12S rRNA gene of mtDNA and are thus matern...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Lee, Seungmin, Rose, Simon, Metodiev, Metodi D., Becker, Lore, Vernaleken, Alexandra, Klopstock, Thomas, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě De Angelis, Martin, Douthwaite, Stephen, Larsson, Nils-Göran
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664167/
https://ncbi.nlm.nih.gov/pubmed/26464487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv427
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados