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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
The innate immune system is critical for the early detection of invading pathogens and for initiating cellular host defence countermeasures, which include the production of type I interferon (IFN)(1–3). However, little is known about how the innate immune system is galvanized to respond to DNA-based...
Uloženo v:
| Vydáno v: | Nature |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664154/ https://ncbi.nlm.nih.gov/pubmed/19776740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08476 |
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