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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

The innate immune system is critical for the early detection of invading pathogens and for initiating cellular host defence countermeasures, which include the production of type I interferon (IFN)(1–3). However, little is known about how the innate immune system is galvanized to respond to DNA-based...

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Dades bibliogràfiques
Publicat a:Nature
Autors principals: Ishikawa, Hiroki, Ma, Zhe, Barber, Glen N.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664154/
https://ncbi.nlm.nih.gov/pubmed/19776740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08476
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