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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
The innate immune system is critical for the early detection of invading pathogens and for initiating cellular host defence countermeasures, which include the production of type I interferon (IFN)(1–3). However, little is known about how the innate immune system is galvanized to respond to DNA-based...
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| Publicado no: | Nature |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664154/ https://ncbi.nlm.nih.gov/pubmed/19776740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08476 |
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