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The STING pathway and regulation of innate immune signaling in response to DNA pathogens

The innate immune system has evolved a variety of sensing mechanisms to detect and counter microbial invasion. These include the Toll-like receptor (TLR), cytoplasmic, nucleotide binding oligomerization domain (NOD)-like receptor and RIG-I-like helicase (RLH) pathways. However, how the cell detects...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ishikawa, Hiroki, Barber, Glen N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SP Birkhäuser Verlag Basel 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056141/
https://ncbi.nlm.nih.gov/pubmed/21161320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0605-2
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