Development of a novel neuroprotective strategy: Combined treatment with hypothermia and valproic acid improves survival in hypoxic hippocampal cells

BACKGROUND: Therapeutic hypothermia and histone deacetylase inhibitors, such as valproic acid (VPA), independently have been shown to have neuroprotective properties in models of cerebral ischemic and traumatic brain injury. However, the depth of hypothermia and the dose of VPA needed to achieve the...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Surgery
Hlavní autoři: Jin, Guang, Liu, Baoling, You, Zerong, Bambakidis, Ted, Dekker, Simone E., Maxwell, Jake, Halaweish, Ihab, Linzel, Durk, Alam, Hasan B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663684/
https://ncbi.nlm.nih.gov/pubmed/24950983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2014.03.038
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky