Development of a novel neuroprotective strategy: Combined treatment with hypothermia and valproic acid improves survival in hypoxic hippocampal cells

BACKGROUND: Therapeutic hypothermia and histone deacetylase inhibitors, such as valproic acid (VPA), independently have been shown to have neuroprotective properties in models of cerebral ischemic and traumatic brain injury. However, the depth of hypothermia and the dose of VPA needed to achieve the...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Surgery
Asıl Yazarlar: Jin, Guang, Liu, Baoling, You, Zerong, Bambakidis, Ted, Dekker, Simone E., Maxwell, Jake, Halaweish, Ihab, Linzel, Durk, Alam, Hasan B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663684/
https://ncbi.nlm.nih.gov/pubmed/24950983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2014.03.038
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