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Normal cardiac contraction in mice lacking the proline-alanine rich region and C1 domain of cardiac myosin binding protein C.

Cardiac myosin binding protein C (cMyBP-C) is an essential regulator of cross bridge cycling. Through mechanisms that are incompletely understood the N-terminal domains (NTDs) of cMyBP-C can activate contraction even in the absence of calcium and can also inhibit cross bridge kinetics in the presenc...

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Pubblicato in:J Mol Cell Cardiol
Autori principali: van Dijk, Sabine J., Witt, Christian C., Harris, Samantha P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663077/
https://ncbi.nlm.nih.gov/pubmed/26455481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.09.006
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