Trimester-Specific Population Pharmacokinetics and Other Correlates of Variability in Sulphadoxine–Pyrimethamine Disposition Among Ugandan Pregnant Women

BACKGROUND: Sulphadoxine–pyrimethamine (SP) is widely used as an intermittent preventive treatment for malaria in pregnancy (IPTp). However, pharmacokinetic studies in pregnancy show variable and often contradictory findings. We describe population and trimester-specific differences in SP pharmacoki...

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Veröffentlicht in:Drugs R D
Hauptverfasser: Odongo, Charles O., Bisaso, Kuteesa R., Ntale, Muhammad, Odia, Gordon, Ojara, Francis W., Byamugisha, Josaphat, Mukonzo, Jackson K., Obua, Celestino
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2015
Schlagworte:
Original Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662941/
https://ncbi.nlm.nih.gov/pubmed/26586482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-015-0110-z
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