Trimester-Specific Population Pharmacokinetics and Other Correlates of Variability in Sulphadoxine–Pyrimethamine Disposition Among Ugandan Pregnant Women

BACKGROUND: Sulphadoxine–pyrimethamine (SP) is widely used as an intermittent preventive treatment for malaria in pregnancy (IPTp). However, pharmacokinetic studies in pregnancy show variable and often contradictory findings. We describe population and trimester-specific differences in SP pharmacoki...

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Publicado en:Drugs R D
Autores principales: Odongo, Charles O., Bisaso, Kuteesa R., Ntale, Muhammad, Odia, Gordon, Ojara, Francis W., Byamugisha, Josaphat, Mukonzo, Jackson K., Obua, Celestino
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2015
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Original Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662941/
https://ncbi.nlm.nih.gov/pubmed/26586482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-015-0110-z
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