Trimester-Specific Population Pharmacokinetics and Other Correlates of Variability in Sulphadoxine–Pyrimethamine Disposition Among Ugandan Pregnant Women

BACKGROUND: Sulphadoxine–pyrimethamine (SP) is widely used as an intermittent preventive treatment for malaria in pregnancy (IPTp). However, pharmacokinetic studies in pregnancy show variable and often contradictory findings. We describe population and trimester-specific differences in SP pharmacoki...

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Publicat a:Drugs R D
Autors principals: Odongo, Charles O., Bisaso, Kuteesa R., Ntale, Muhammad, Odia, Gordon, Ojara, Francis W., Byamugisha, Josaphat, Mukonzo, Jackson K., Obua, Celestino
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2015
Matèries:
Original Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662941/
https://ncbi.nlm.nih.gov/pubmed/26586482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-015-0110-z
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