Trimester-Specific Population Pharmacokinetics and Other Correlates of Variability in Sulphadoxine–Pyrimethamine Disposition Among Ugandan Pregnant Women

BACKGROUND: Sulphadoxine–pyrimethamine (SP) is widely used as an intermittent preventive treatment for malaria in pregnancy (IPTp). However, pharmacokinetic studies in pregnancy show variable and often contradictory findings. We describe population and trimester-specific differences in SP pharmacoki...

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Detalhes bibliográficos
Publicado no:Drugs R D
Main Authors: Odongo, Charles O., Bisaso, Kuteesa R., Ntale, Muhammad, Odia, Gordon, Ojara, Francis W., Byamugisha, Josaphat, Mukonzo, Jackson K., Obua, Celestino
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662941/
https://ncbi.nlm.nih.gov/pubmed/26586482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-015-0110-z
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