ATM and ATR signalling regulate the recruitment of human telomerase to telomeres

The yeast homologues of the ATM and ATR DNA damage response kinases play key roles in telomerase-mediated telomere maintenance, but the role of ATM/ATR in the mammalian telomerase pathway has been less clear. Here we demonstrate the requirement for ATM and ATR in the localization of telomerase to te...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Tong, Adrian S., Stern, J. Lewis, Sfeir, Agnel, Kartawinata, Melissa, de Lange, Titia, Zhu, Xu-Dong, Bryan, Tracy M.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662887/
https://ncbi.nlm.nih.gov/pubmed/26586433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.041
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