Prolyl isomerase Pin1 regulates axon guidance by stabilizing CRMP2A selectively in distal axons

Axon guidance relies on precise translation of the gradients of the extracellular signals into local changes of cytoskeletal dynamics, but the molecular mechanisms regulating dose-dependent responses of growth cones are still poorly understood. Here we show that during embryonic development in growi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Balastik, Martin, Zhou, Xiao Zhen, Alberich-Jorda, Meritxell, Weissova, Romana, Žiak, Jakub, Pazyra-Murphy, Maria F., Cosker, Katharina E, Machonova, Olga, Kozmikova, Iryna, Chen, Chun-Hau, Pastorino, Lucia, Asara, John M., Cole, Adam, Sutherland, Calum, Segal, Rosalind A., Lu, Kun Ping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662601/
https://ncbi.nlm.nih.gov/pubmed/26489457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.026
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