Prolyl isomerase Pin1 regulates axon guidance by stabilizing CRMP2A selectively in distal axons

Axon guidance relies on precise translation of the gradients of the extracellular signals into local changes of cytoskeletal dynamics, but the molecular mechanisms regulating dose-dependent responses of growth cones are still poorly understood. Here we show that during embryonic development in growi...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Balastik, Martin, Zhou, Xiao Zhen, Alberich-Jorda, Meritxell, Weissova, Romana, Žiak, Jakub, Pazyra-Murphy, Maria F., Cosker, Katharina E, Machonova, Olga, Kozmikova, Iryna, Chen, Chun-Hau, Pastorino, Lucia, Asara, John M., Cole, Adam, Sutherland, Calum, Segal, Rosalind A., Lu, Kun Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662601/
https://ncbi.nlm.nih.gov/pubmed/26489457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.026
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