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Targeting Cathepsin B for Cancer Therapies

Cathepsin B is a member of the papain family of cysteine proteases normally present in the lysosome, but it can translocate and function to degrade components of the extracellular matrix. It exhibits carboxyopeptidase, peptidyldipepidase, and endopeptidase activity. Aberrant overexpression of cathep...

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Bibliographic Details
Published in:Horiz Cancer Res
Main Authors: Ruan, Hang, Hao, Susan, Young, Peter, Zhang, Hongtao
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662557/
https://ncbi.nlm.nih.gov/pubmed/26623174
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