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Cathepsin B-cleavable doxorubicin prodrugs for targeted cancer therapy
Doxorubicin (DOX) is one of the most effective cytotoxic anticancer drugs used for the treatment of hematological malignancies, as well as a broad range of solid tumors. However, the clinical applications of this drug have long been limited due to its severe dose-dependent toxicities. Therefore, DOX...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
D.A. Spandidos
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583876/ https://ncbi.nlm.nih.gov/pubmed/23291656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1754 |
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