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Cathepsin B-cleavable doxorubicin prodrugs for targeted cancer therapy

Doxorubicin (DOX) is one of the most effective cytotoxic anticancer drugs used for the treatment of hematological malignancies, as well as a broad range of solid tumors. However, the clinical applications of this drug have long been limited due to its severe dose-dependent toxicities. Therefore, DOX...

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Detalhes bibliográficos
Main Authors: ZHONG, YAN-JUN, SHAO, LI-HUA, LI, YAN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583876/
https://ncbi.nlm.nih.gov/pubmed/23291656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1754
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