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Cathepsin L targeting in cancer treatment

Proteolytic enzymes may serve as promising targets for novel therapeutic treatment strategies seeking to impede cancer progression and metastasis. One such enzyme is cathepsin L (CTSL), a lysosomal cysteine protease. CTSL upregulation, a common occurrence in a variety of human cancers, has been wide...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Sudhan, Dhivya R., Siemann, Dietmar W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624022/
https://ncbi.nlm.nih.gov/pubmed/26299995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2015.08.007
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