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Cathepsin L secretion by host and neoplastic cells potentiates invasion

The presence of macrophages within breast tumors correlates with metastatic potential. These tumor-associated macrophages often take on a pro-tumorigenic (M2-like) phenotype resulting in the secretion of growth factors and proteases, including the lysosomal protease cathepsin L. Since cathepsin L al...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dykes, Samantha S., Fasanya, Henrietta O., Siemann, Dietmar W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756864/
https://ncbi.nlm.nih.gov/pubmed/31565189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27182
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