Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis

INTRODUCTION: Sepsis is an exaggerated and dysfunctional immune response to infection. Activation of innate immunity recognition systems including complement and the Toll-like receptor family initiate this disproportionate inflammatory response. The aim of this study was to explore the effect of com...

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Foilsithe in:Crit Care
Main Authors: Skjeflo, Espen W., Sagatun, Caroline, Dybwik, Knut, Aam, Sturla, Urving, Sven H., Nunn, Miles A., Fure, Hilde, Lau, Corinna, Brekke, Ole-Lars, Huber-Lang, Markus, Espevik, Terje, Barratt-Due, Andreas, Nielsen, Erik W., Mollnes, Tom E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662001/
https://ncbi.nlm.nih.gov/pubmed/26612199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-1129-9
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