CD14 and Complement Crosstalk and Largely Mediate the Transcriptional Response to Escherichia coli in Human Whole Blood as Revealed by DNA Microarray

Systemic inflammation like in sepsis is still lacking specific diagnostic markers and effective therapeutics. The first line of defense against intruding pathogens and endogenous damage signals is pattern recognition by e.g., complement and Toll-like receptors (TLR). Combined inhibition of a key com...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lau, Corinna, Nygård, Ståle, Fure, Hilde, Olstad, Ole Kristoffer, Holden, Marit, Lappegård, Knut Tore, Brekke, Ole-Lars, Espevik, Terje, Hovig, Eivind, Mollnes, Tom Eirik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338229/
https://ncbi.nlm.nih.gov/pubmed/25706641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117261
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