Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis

Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability. BTR complex, composed of BLM, to...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Xu, Chang, Wang, Yan, Wang, Lu, Wang, Qin, Du, Li-Qing, Fan, Saijun, Liu, Qiang, Li, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661824/
https://ncbi.nlm.nih.gov/pubmed/26556339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161125965
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