Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles

The alternative pathway of complement is an important part of the innate immunity response against foreign particles invading the human body. To avoid damage to host cells, it needs to be efficiently down-regulated by plasma factor H (FH) as exemplified by various diseases caused by mutations in its...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Haapasalo, Karita, van Kessel, Kok, Nissilä, Eija, Metso, Jari, Johansson, Tiira, Miettinen, Sini, Varjosalo, Markku, Kirveskari, Juha, Kuusela, Pentti, Chroni, Angelika, Jauhiainen, Matti, van Strijp, Jos, Jokiranta, T. Sakari
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661410/
https://ncbi.nlm.nih.gov/pubmed/26468283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669226
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