Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles

The alternative pathway of complement is an important part of the innate immunity response against foreign particles invading the human body. To avoid damage to host cells, it needs to be efficiently down-regulated by plasma factor H (FH) as exemplified by various diseases caused by mutations in its...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Haapasalo, Karita, van Kessel, Kok, Nissilä, Eija, Metso, Jari, Johansson, Tiira, Miettinen, Sini, Varjosalo, Markku, Kirveskari, Juha, Kuusela, Pentti, Chroni, Angelika, Jauhiainen, Matti, van Strijp, Jos, Jokiranta, T. Sakari
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661410/
https://ncbi.nlm.nih.gov/pubmed/26468283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669226
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