The Polarized Effect of Intracellular Calcium on the Renal Epithelial Sodium Channel Occurs as a Result of Subcellular Calcium Signaling Domains Maintained by Mitochondria

The renal epithelial sodium channel (ENaC) provides regulated sodium transport in the distal nephron. The effects of intracellular calcium ([Ca(2+)](i)) on this channel are only beginning to be elucidated. It appears from previous studies that the [Ca(2+)](i) increases downstream of ATP administrati...

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Publicado en:J Biol Chem
Autores principales: Thai, Tiffany L., Yu, Ling, Galarza-Paez, Laura, Wu, Ming Ming, Lam, Ho Yin Colin, Bao, Hui Fang, Duke, Billie Jeanne, Al-Khalili, Otor, Ma, He-Ping, Liu, Bingchen, Eaton, Douglas C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661396/
https://ncbi.nlm.nih.gov/pubmed/26451045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.668293
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