Á lódáil...

Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib

Mechanism-based inactivation (MBI) of CYP450 enzymes is a unique form of inhibition in which the enzymatic machinery of the victim is responsible for generation of the reactive metabolite. This precondition sets up a time-dependency for the inactivation process, a hallmark feature that characterizes...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Drug Metab Rev
Main Authors: Ho, Han Kiat, Chan, Chun Yip, Hardy, Klarissa D, Chan, Eric Chun Yong
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661142/
https://ncbi.nlm.nih.gov/pubmed/25639891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602532.2014.1003648
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!