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HIGH PRESSURE PROMOTES ALPHA-SYNUCLEIN AGGREGATION IN CULTURED NEURONAL CELLS

A-Synuclein is found in plaques associated with Parkinson’s and other neurodegenerative diseases. Changes in α-synuclein oligomerization are thought to give rise to nucleation of neurodegenerative plaques. Here, we investigated the effect of hydrostatic pressure on the aggregation of α-synuclein in...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Golebiewska, Urszula, Scarlata, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661088/
https://ncbi.nlm.nih.gov/pubmed/26434717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.09.019
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