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Linking Alpha-Synuclein Properties with Oxidation: A hypothesis on a mechanism underling cellular aggregation
α-Synuclein is a small, natively unstructured protein with propensity to aggregate. α-Synuclein fibrils are major components of Lewy bodies that are hallmarks of many neurodegenerative diseases. The solution properties and aggregation behavior of α-synuclein has been well characterized, but despite...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000690/ https://ncbi.nlm.nih.gov/pubmed/24474217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-014-9540-5 |
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