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Investigation of the role of stereoelectronic effects in the conformation of piperidones by NMR spectroscopy and X-ray diffraction

This paper reports the synthesis of a series of piperidones 1–8 by the Mannich reaction and analysis of their structures and conformations in solution by NMR and mass spectrometry. The six-membered rings in 2,4,6,8-tetraphenyl-3,7-diazabicyclo[3.3.1]nonan-9-ones, compounds 1 and 2, adopt a chair–boa...

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Библиографические подробности
Опубликовано в: :Beilstein J Org Chem
Главные авторы: Garcias-Morales, Cesar, Ortegón-Reyna, David, Ariza-Castolo, Armando
Формат: Artigo
Язык:Inglês
Опубликовано: Beilstein-Institut 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660988/
https://ncbi.nlm.nih.gov/pubmed/26664617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.213
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