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Rescue from tau-induced neuronal dysfunction produces insoluble tau oligomers
Aggregation of highly phosphorylated tau is a hallmark of Alzheimer’s disease and other tauopathies. Nevertheless, animal models demonstrate that tau-mediated dysfunction/toxicity may not require large tau aggregates but instead may be caused by soluble hyper-phosphorylated tau or by small tau oligo...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4660438/ https://ncbi.nlm.nih.gov/pubmed/26608845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17191 |
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