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Microtubule stabilising peptides rescue tau phenotypes in-vivo

The microtubule cytoskeleton is a highly dynamic, filamentous network underpinning cellular structure and function. In Alzheimer’s disease, the microtubule cytoskeleton is compromised, leading to neuronal dysfunction and eventually cell death. There are currently no disease-modifying therapies to sl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Quraishe, Shmma, Sealey, Megan, Cranfield, Louise, Mudher, Amritpal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133624/
https://ncbi.nlm.nih.gov/pubmed/27910888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38224
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