Functional dynamics within the human ribosome regulate the rate of active protein synthesis

The regulation of protein synthesis contributes to gene expression in both normal physiology and disease, yet kinetic investigations of the human translation mechanism are currently lacking. Using single-molecule fluorescence imaging methods, we have quantified the nature and timing of structural pr...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Ferguson, Angelica, Wang, Leyi, Altman, Roger B., Terry, Daniel S., Juette, Manuel F., Burnett, Benjamin J., Alejo, Jose L., Dass, Randall A., Parks, Matthew M., Vincent, Theresa C., Blanchard, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660248/
https://ncbi.nlm.nih.gov/pubmed/26593721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.09.013
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