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The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling

Accurate segregation of chromosomes during cell division is essential. The Dam1 complex binds kinetochores to microtubules and its oligomerization is required to form strong attachments. It is a key target of Aurora B kinase, which destabilizes erroneous attachments allowing subsequent correction. U...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Zelter, Alex, Bonomi, Massimiliano, Kim, Jae ook, Umbreit, Neil T., Hoopmann, Michael R., Johnson, Richard, Riffle, Michael, Jaschob, Daniel, MacCoss, Michael J., Moritz, Robert L., Davis, Trisha N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660060/
https://ncbi.nlm.nih.gov/pubmed/26560693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9673
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