The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling

Accurate segregation of chromosomes during cell division is essential. The Dam1 complex binds kinetochores to microtubules and its oligomerization is required to form strong attachments. It is a key target of Aurora B kinase, which destabilizes erroneous attachments allowing subsequent correction. U...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zelter, Alex, Bonomi, Massimiliano, Kim, Jae ook, Umbreit, Neil T., Hoopmann, Michael R., Johnson, Richard, Riffle, Michael, Jaschob, Daniel, MacCoss, Michael J., Moritz, Robert L., Davis, Trisha N.
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660060/
https://ncbi.nlm.nih.gov/pubmed/26560693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9673
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