Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

In autoimmune type 1 diabetes mellitus (T1D), auto-reactive clones of CD4(+) and CD8(+) T lymphocytes in the periphery evolve into pancreas-infiltrating T lymphocytes (PILs), which destroy insulin-producing beta-cells through inflammatory insulitis. Previously, we demonstrated that, during the devel...

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Pubblicato in:PLoS One
Autori principali: Fornari, Thais A., Donate, Paula B., Assis, Amanda F., Macedo, Claudia, Sakamoto-Hojo, Elza T., Donadi, Eduardo A., Passos, Geraldo A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659659/
https://ncbi.nlm.nih.gov/pubmed/26606254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142688
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