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Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies
The aim of this study is to develop a sensitive UPLC-MS/MS method to quantify columbin in biological sample. Chromatographic separation was accomplished using Waters UPLC BEH C(18) column with acetonitrile and 0.1% of formic acid in water as the mobile phases. The mass analysis was performed on an A...
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| Опубликовано в: : | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4659646/ https://ncbi.nlm.nih.gov/pubmed/26295697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.07.030 |
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