REDUCTION OF AMYLOID-BETA LEVELS IN MOUSE EYE TISSUES BY INTRA-VITREALLY DELIVERED NEPRILYSIN

Amyloid-beta (Aβ) is a group of aggregation-prone, 38- to 43-amino acid peptides generated in the eye and other organs. Numerous studies suggest that the excessive build-up of low-molecular-weight soluble oligomers of Aβ plays a role in the progression of Alzheimer’s disease and other brain degenera...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Parthasarathy, Rajni, Chow, K. Martin, Derafshi, Zahra, Fautsch, Michael P., Hetling, John R., Rodgers, David W., Hersh, Louis B., Pepperberg, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659645/
https://ncbi.nlm.nih.gov/pubmed/26142956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.06.027
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