MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma

BACKGROUND: No reliable predictors of susceptibility to gemcitabine chemotherapy exist in pancreatic ductal adenocarcinoma (PDAC). MicroRNAs (miR) are epigenetic gene regulators with tumorsuppressive or oncogenic roles in various carcinomas. This study assesses chemoresistant PDAC for its specific m...

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Pubblicato in:PLoS One
Autori principali: Dhayat, Sameer A., Mardin, Wolf Arif, Seggewiß, Jochen, Ströse, Anda Jana, Matuszcak, Christiane, Hummel, Richard, Senninger, Norbert, Mees, Sören Torge, Haier, Jörg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659591/
https://ncbi.nlm.nih.gov/pubmed/26606261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143755
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