MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma

BACKGROUND: No reliable predictors of susceptibility to gemcitabine chemotherapy exist in pancreatic ductal adenocarcinoma (PDAC). MicroRNAs (miR) are epigenetic gene regulators with tumorsuppressive or oncogenic roles in various carcinomas. This study assesses chemoresistant PDAC for its specific m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dhayat, Sameer A., Mardin, Wolf Arif, Seggewiß, Jochen, Ströse, Anda Jana, Matuszcak, Christiane, Hummel, Richard, Senninger, Norbert, Mees, Sören Torge, Haier, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659591/
https://ncbi.nlm.nih.gov/pubmed/26606261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143755
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