MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma

BACKGROUND: No reliable predictors of susceptibility to gemcitabine chemotherapy exist in pancreatic ductal adenocarcinoma (PDAC). MicroRNAs (miR) are epigenetic gene regulators with tumorsuppressive or oncogenic roles in various carcinomas. This study assesses chemoresistant PDAC for its specific m...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Dhayat, Sameer A., Mardin, Wolf Arif, Seggewiß, Jochen, Ströse, Anda Jana, Matuszcak, Christiane, Hummel, Richard, Senninger, Norbert, Mees, Sören Torge, Haier, Jörg
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659591/
https://ncbi.nlm.nih.gov/pubmed/26606261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143755
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