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Semaphorin 3A activates the guanosine triphosphatase Rab5 to promote growth cone collapse and organize callosal axon projections

Axon guidance (pathfinding) wires the brain during development and is regulated by various attractive and repulsive cues. Semaphorin 3A (Sema3A) is a repulsive cue, inducing the collapse of axon growth cones. In the mammalian forebrain, the corpus callosum is the major commissure that transmits info...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Signal
Egile Nagusiak: Wu, Kong-Yan, He, Miao, Hou, Qiong-Qiong, Sheng, Ai-Li, Yuan, Lei, Liu, Fei, Liu, Wen-Wen, Li, Guangpu, Jiang, Xing-Yu, Luo, Zhen-Ge
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659511/
https://ncbi.nlm.nih.gov/pubmed/25161316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005334
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