Secreted Human Amyloid Precursor Protein Binds Semaphorin 3a and Prevents Semaphorin-Induced Growth Cone Collapse

The amyloid precursor protein (APP) is well known for giving rise to the amyloid-β peptide and for its role in Alzheimer's disease. Much less is known, however, on the physiological roles of APP in the development and plasticity of the central nervous system. We have used phage display of a pep...

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Detalhes bibliográficos
Main Authors: Magdesian, Margaret H., Gralle, Matthias, Guerreiro, Luiz H., Beltrão, Paulo José I., Carvalho, Milena M. V. F., Santos, Luís Eduardo da S., de Mello, Fernando G., Reis, Ricardo A. M., Ferreira, Sérgio T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146505/
https://ncbi.nlm.nih.gov/pubmed/21829538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022857
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