SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth

Neurons and glial cells in the retina contribute to neovascularization, or the formation of abnormal new blood vessels, in proliferative retinopathy, a condition that can lead to vision loss or blindness. We identified a mechanism by which suppressor of cytokine signaling 3 (SOCS3) in neurons and gl...

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Foilsithe in:Sci Signal
Main Authors: Sun, Ye, Ju, Meihua, Lin, Zhiqiang, Fredrick, Thomas W., Evans, Lucy P., Tian, Katherine T., Saba, Nicholas J., Morss, Peyton C., Pu, William T., Chen, Jing, Stahl, Andreas, Joyal, Jean-Sébastien, Smith, Lois E. H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659437/
https://ncbi.nlm.nih.gov/pubmed/26396267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa8695
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