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FGF21 administration suppresses retinal and choroidal neovascularization in mice

Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy and age related macular degeneration. Using a mouse model of hypoxia-driven retinal neovascularization we find that fibroblast growth factor 21 (FGF21) administration suppresses...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Fu, Zhongjie, Gong, Yan, Liegl, Raffael, Wang, Zhongxiao, Liu, Chi-Hsiu, Meng, Steven S., Burnim, Samuel B., Saba, Nicholas J., Fredrick, Thomas W., Morss, Peyton C., Hellstrom, Ann, Talukdar, Saswata, Smith, Lois E.H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328201/
https://ncbi.nlm.nih.gov/pubmed/28199833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.01.014
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