Cytochrome P450 oxidase 2C inhibition adds to ω-3 long-chain polyunsaturated fatty acids protection against retinal and choroidal neovascularization

OBJECTIVE: Pathological ocular neovascularization is a major cause of blindness. Increased dietary intake of ω-3 long-chain polyunsaturated fatty acids (LCPUFA) reduces retinal and choroidal neovascularization, but ω-3 LCPUFA metabolites of a major metabolizing pathway, cytochrome P450 oxidase (CYP)...

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Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Gong, Yan, Fu, Zhongjie, Edin, Matthew L., Liu, Chi-Hsiu, Wang, Zhongxiao, Shao, Zhuo, Fredrick, Thomas W., Saba, Nicholas J., Morss, Peyton C., Burnim, Samuel B., Meng, Steven S., Lih, Fred B., Lee, Kin Sing Stephen, Moran, Elizabeth P., SanGiovanni, John Paul, Hellström, Ann, Hammock, Bruce D., Zeldin, Darryl C., Smith, Lois E. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010176/
https://ncbi.nlm.nih.gov/pubmed/27417579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307558
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