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Nuclear receptor RORα regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation
Pathologic ocular angiogenesis is a leading cause of blindness, influenced by both dysregulated lipid metabolism and inflammation. Retinoic-acid-receptor–related orphan receptor alpha (RORα) is a lipid-sensing nuclear receptor with diverse biologic function including regulation of lipid metabolism a...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547221/ https://ncbi.nlm.nih.gov/pubmed/26243880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504387112 |
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