Nuclear receptor RORα regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation

Pathologic ocular angiogenesis is a leading cause of blindness, influenced by both dysregulated lipid metabolism and inflammation. Retinoic-acid-receptor–related orphan receptor alpha (RORα) is a lipid-sensing nuclear receptor with diverse biologic function including regulation of lipid metabolism a...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Sun, Ye, Liu, Chi-Hsiu, SanGiovanni, John Paul, Evans, Lucy P., Tian, Katherine T., Zhang, Bing, Stahl, Andreas, Pu, William T., Kamenecka, Theodore M., Solt, Laura A., Chen, Jing
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547221/
https://ncbi.nlm.nih.gov/pubmed/26243880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504387112
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