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KSHV induces aerobic glycolysis and angiogenesis through HIF-1-dependent upregulation of pyruvate kinase 2 in Kaposi’s sarcoma

Kaposi’s sarcoma (KS) is a vascular neoplasm caused by infection of endothelial or endothelial precursor cells with the Kaposi’s sarcoma-associated herpesvirus (KSHV/HHV8). Research efforts have focused on defining the molecular events explaining how KSHV promotes pathological angiogenesis and KS tu...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Angiogenesis
Main Authors: Ma, Tao, Patel, Harsh, Babapoor-Farrokhran, Savalan, Franklin, Renty, Semenza, Gregg L., Sodhi, Akrit, Montaner, Silvia
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659376/
https://ncbi.nlm.nih.gov/pubmed/26092770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-015-9475-4
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