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Allylic Selenosulfide Rearrangement: A Method for Chemical Ligation to Cysteine and Other Thiols

Alkylation of potassium selenosulfate with allylic halides gives Se-allyl seleno Bunte salts. On reaction with thiols at room temperature these afford mixed dialkyl selenosulfides, which undergo 2,3-sigmatropic rearrangement with loss of selenium, either spontaneously or with assistance by triphenyl...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Crich, David, Krishnamurthy, Venkataramanan, Hutton, Thomas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658652/
https://ncbi.nlm.nih.gov/pubmed/16492032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja057521c
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