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A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology

Target-guided synthesis is an approach to drug discovery that allows the target to self-assemble its own binding agents. So far, target-guided synthesis and especially in situ click chemistry have attracted extensive attention and have led to the identification of highly potent inhibitors for protei...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Hu, Ming-Hao, Chen, Xiao, Chen, Shuo-Bin, Ou, Tian-Miao, Yao, Meicun, Gu, Lian-Quan, Huang, Zhi-Shu, Tan, Jia-Heng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658637/
https://ncbi.nlm.nih.gov/pubmed/26603780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17202
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