Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry

[Image: see text] Modern combinatorial chemistry is used to discover compounds with desired function by an alternative strategy, in which the biological target is directly involved in the choice of ligands assembled from a pool of smaller fragments. Herein, we present the first experimental result w...

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Detalhes bibliográficos
Main Authors: Peruzzotti, Cristina, Borrelli, Stella, Ventura, Micol, Pantano, Rebecca, Fumagalli, Gaia, Christodoulou, Michael S., Monticelli, Damiano, Luzzani, Marcello, Fallacara, Anna Lucia, Tintori, Cristina, Botta, Maurizio, Passarella, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027485/
https://ncbi.nlm.nih.gov/pubmed/24900659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300394w
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